Vitiligo - problem solved
Hormonal "sea" overflows its banks
Psoriasis keep "in check"
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"Rose of the Devil"
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Currently, there are several theories of the pathogenesis of vitiligo.
Theories of the pathogenesis of vitiligo
The neurogenic theory.
her father for - is considered to be Lerner A. The basis of the theory in 1959, he put a known fact the unity of origin of nerve cells and melanocytes from the neural crest ectoderm and the fact that both types of cells is used for secretion of its most important product (first - catecholamines, the second - melanin) The same starting material - tyrosine.
In support of this theory, presented numerous clinical observations, indicating a connection with depigmentation disorders of the nervous system, as well as various experimental, pathophysiologic, and pathologic al. Study.
However, the results of the practical study of the state of the peripheral nervous system were not as convincing as theoretical background. Despite the presence of changes in its functions, the adherents of the theory have not been able to reach an agreement the final decision due to data inconsistencies.
The immune theory.
It has been discussed for almost 40 years. Its founder is considered Lorincz A., who in 1959, the first time suggested that the basis of vitiligo is autoserotherapy to pathologically altered melanocytes or tyrosinase.
In recent decades, leading experts [Ortonne J.-P. . Et al, 1983] presented this theory in two versions, one of which involves an immune defect autoserotherapy primary and second - acquired defect of melanocytes and secondary autoserotherapy. Moreover, in both cases, the main damaging agent melanocytes autoantibodies. Therefore, it is the detection of antibodies against melanocytes has long been considered the main proof of this theory.
However, despite numerous studies carried out in support of the theory of autoimmune vitiligo, especially in 80-years of the twentieth century [Grimes HE et al, 1983.; Takei M. et al, 1984.; Moellmann G. et al, 1985.; Naughton GK et al, 1986.; Norris DA et al, 1988.; Badri AM et al. 1993] reliable evidence of specific autosensibilization to pigment cells not derived in vitiligo. In recent years, research activity in this area decreased markedly.
The theory of self-destruction.
According to her, the destruction of melanocytes in vitiligo occurs either due to the toxic effect of metabolites of substances involved in the process of melanogenesis, or due to a violation of regulation in the mechanism that controls the normal destruction of melanosomes. The origins of this theory were Bleehen S. et al. [1965] and Pathak M. et al. [1966], who believed that the destruction of melanocytes occurs as a result of the formation of free radicals in phenolic compounds. However, this theory, despite its originality and theoretical validity, is practically not confirmed by any experimental and clinical data and now has almost no supporters.
Hereditary theory.
It's not even a theory, and opinion about the genetic nature of vitiligo, which adhere to Indian authors most [Bhatia PS, 1992]. However, all available data on the subject, can never serve as an indication for a specific inheritance of the disease, especially since earlier attempts carried out to allocate a specific type of vitiligo inheritance and reliable result and did not give.
Behavioral theory.
It is the result of the analysis of the world's scientific literature data vitiligo - is not an easy dyschromia, not some kind of cosmetic defect (as it is often assessed dermatologists), and complex psychosomatic disease of the whole organism. It is on a par with such well-known dermatoses as alopecia Areata, neyroder-mit, vulgar psoriasis, etc. ..
Vitiligo has its principal features.
- 1. This disease does not occur at all in a row, but only certain people have the constitutional type - " Pitt"- Fire (aka" choleric ") having a number of features of psychological, autonomic and immune response.
- 2. Vitiligo never starts just like that, for no reason, no reason at all (although the patient is so in most cases, and it seems). Depigmentation of the skin always occurs only when you hit the predisposed individual (and at any age) in some unfavorable conditions. And the impetus, an incentive to top the disease can serve as both external and internal factors.
Of foreign It should be noted:
- a) nervous stress, psychological overload, moral injury;
- b) physical, chemical and radiation (UV) injury.
- Of Internal- Toxic (infectious, chemical, and medical origin) and endocrine.
Especially it is necessary to emphasize that a healthy organism usually copes well with such troubles. The appearance of depigmentation is possible only if the listed adverse effects lie, so to speak, on the prepared soil. Such a "soil", in this case, is the physiological imbalance of the organism towards the predominance of uncharacteristic natural properties and qualities, and its cause is the violation of living conditions (regime, sleep, nutrition, etc.). This imbalance contributes, on the one hand, to increasing the sensitivity of the skin to external stimuli, and on the other hand, to unbalancing the psychological, vegetative and immune responses.
As a result, the most annoying places in these individuals increased activity of specific immune cells, as a result of that damage melanocytes and develops focal depigmentation.
- 3. A third and very important feature of vitiligo is that all general and local immune disorders, autonomic and psychological (depigmentation, increased activity of cellular immunity in the skin, increased sympathetic tone in the skin and general vegetative imbalanceSocio-psychological maladjustment of personality) are interconnected in a sort of "vicious circle". In it, each of these mechanisms stimulate each other and maintained stimulation (scheme).
This feature provides Vitiligo its long existence and the lack of efficiency in the conventional treatment (which, at best, only directed to the stimulation of melanogenesis) is not only reducing its effectiveness, but also negates all efforts of doctors after his termination.
- 4. The latter feature of vitiligo regard individual personality traits most of the individuals suffering from vitiligo (mostly women). We are talking about a special sensitivity to their cosmetic defect, which for - is essentially for vitiligo patients. This is reflected in the end that his patients psychological experiences as it were, "wind the" Statement disease. The more they suffer, the worse the disease, the faster the progress depigmentation of the skin.
Adhering to the latter theory is more logical and comprehensive, our center offers a comprehensive treatment that will apply to all of the pathogenesis of this disease.
Means of treatment of vitiligo:
- a). Removal of imbalance of the autonomic nervous system.
Knowing that these disorders are associated with the Pitt-dosha (fire) imbalance in the body, which is characteristic of very energetic, energetic, temperamental, aggressive, angry, explosive personalities, we must direct our actions in two main directions. The first is to take phytopreparations that regulate the balance of the vegetative NA, which give a sedative, sedative effect. Such as Amrit Rasayana, Brami Vati, Swamala, ashwagandha and more
Second - do not unbalance correction VNS medical methods: psychotherapy, auto-training, yoga, meditation, adjustment mode of life (work, rest, sleep, Piethen).
- b) Stabilization of immune disorders.
Drugs used for this purpose, eliminating the autoimmune processes in the body. Ayurvedic medicines are used " Him Guard "," Varna - Prasad"- A unique product. TurmericEntering into its structure, improves the complexion, cleanses the skin, sweat glands open. Turmeric is used to eliminate itching, dermatitis, allergic rashes. Turmeric extract is used as a remedy for skin lesions to heal wounds. Tissue repair and wound healing - a complex process, including a phenomenon inflammation, granulation and regeneration fabrics; the beneficial properties of turmeric, manifested in these processes, have turned it into one of the effects-governmental wound healing therapeutic agents for the treatment of all tissue repair processes. Some authors have demonstrated inhibitory effect on the metabolism of arachidonic turmeric acid, Showed beneficial in skin diseases such as psoriasis. It has been shown that turmeric is very effective for the prevention and treatment of skin cancer due to the inhibitory effect on the oxidation of epidermal DNA and modulating the genetic manifestations of induced proto-oncogenes by various carcinogenic agents. It was observed that turmeric inhibits epidermal cyclooxygenase and lipoxidase, enzymes that activate benzopyrene, weakening the covalent bond of benzopyrene with epidermal DNA. This is an indication of the potential phototoxicity of turmeric that can be used to treat skin diseases such as psoriasis, bacterial infections, cancer and viral infections. BasilIn its structure, successfully fights free radicals, perfectly tones skin, smoothes fine lines.
Juniper promotes regeneration of skin cells, heals wounds and ulcers, prevents the growth of scar tissue, eliminates stretch marks and cellulite, improves skin elasticity, it eliminates laxity, lethargy, impure color and weary look. Oregano successfully cures eczema, pruritic dermatoses, pustular rash. Fennel increases the elasticity of the epidermis, renews the skin, giving it a homogeneous color.
To reduce the activity of cell-mediated immunity in the skin and at the same time targeted stimulation of follicular melanocytes held sparing technique photochemotherapy of vitiligo, which is a combination of individualized doses of ultraviolet radiation lesions with furokumarinovymi drugs (Rsoberanum, Ammifurin, Beroksan, psoralen, etc.). and antioxidants ( Win Vita, Basil, Amrit Rasayana and etc.).
- at) Correction of the general condition of the body
This is best suited ancient Vedic system of natural healing (correction of the balance of the doshas of the body), adapted to modern conditions, and includes the approaches and methods, balancing the functions of all organs and systems, and applied taking into account the constitutional body type, time of day, season. A study carried out by the apparatus "Veda Pulse", According to the pulse diagnosis is determined the state of the doshas in the body (vikriti), the state of balance of the autonomic nervous system adaptation and mobilization capacity of the organism, the optimal mode for the given period (life and behavior); fitoretsepty; special physical and breathing exercises; water treatment; Individual power under the constitution; Oil and point self-massage; aromatherapy; Complex seasonal cleanse the body.
- d) Preventive measures
It is in compliance with domestic gentle treatment aimed at eliminating the adverse effects that provoke the emergence and spread of new lesions on the skin. Antiparasitic treatment of seasonal (giardiasis, helminthiasis) - Fung drugs Acura, Chanterelles and Ayurvedic herbal remedies wing, Didan Jadidsyrup crimini and others. Because parasites play an important role in the failure of metabolism.
For the prevention of psychological disorders are also preparation is the treatment of vitiligo - cosmetic products and methods, masking cosmetic defect (rubbing a paste of turmeric and furokumarinovyh solutions, etc.).
We wish you good health, happiness and patience!
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